Orlance, Inc., headquartered in Seattle, WA, is developing its MACH-1® platform to deliver nucleic acid vaccines and related therapies without cold chain restrictions. Leveraging $9.6M in NIH SBIR funding, Orlance has developed the MACH-1 platform to intradermally deliver stable, powdered vaccines in a needle-free manner that minimizes dose size, eliminates cold chain requirements, and is poised to increase access and compliance. The company’s executive team comprises significant immunology, vaccinology, biotech development, bioengineering, regulatory and partnering experience and is well poised to bring its preclinical assets to IND and Phase 1 readiness in 2021.
25 years of bioengineering, innovation development, regulatory and clinical affairs, product launch, VC and executive experience.
co-inventor of MACH-1 technology, formerly at PowderJect, UW Professor, the lab focuses on NA vaccines for multiple pathogens.
co-founder and SAB member, UW, molecular and computational approaches vaccine design, the originator of conserved element (CE) approach to vaccine development.
15 years in NA vaccine field, developed genetic adjuvant platform at Profectus Biosciences, Inc.
Bioengineer, Immunology, and nano delivery system experience.